Wimbledon gets down to business in second week with Williams missing

With no play on the middle Sunday a sacred tradition which has only been violated in 1991, 1997 and 2004, completing the Saturday schedule fell short by two matches.

In one, Australian open winner Stan Wawrinka will face Denis Istomin before taking on the winner from John Isner and Feliciano Lopez.

The rest of the fourth round was completed on schedule, with five-time champion Serena Williams humbled in three sets by Alize Cornet.

The French winner will next play Canadian 13th seed Eugenie Bouchard, a grand slam semi-finalist at Melbourne and Paris so far this season.

"Cornet is playing good tennis, and I'm looking forward to a battle on Monday," said Bouchard. "I'll focus on my side of the net, that's when I play my best.

"I know I'm going to fight to the end and stay positive, try to keep playing as well as I can."

The men's lineup looks stable, with top seed Novak Djokovic due to play Frenchman Jo-Wilfried Tsonga.

Djokovic rolled onto his left shoulder in the previous round and happily took two days of weekend rest.

"There is no major damage which means that I'm quite confident that it will not affect my physical state or regimen or daily routine.

"I think it's going to be fine. Doctors told me usually in these cases you might feel soreness in the next couple of days.

"But I can play around with practices and recovery and see how it goes.  But I'm quite confident it's going to be all right for next one."

Second seed Rafael Nadal faces Australian wild card Nick Kyrgios, making the first big step of his career.

The Spaniard, who lost the opening set of all three of his week one wins, is still pleased to have gone through.

"In one way it's very positive to have work already done. I'm playing well, I'd be lying if I say another thing.  But this surface is open opportunity to everybody because the matches can be very close.  That's what happens."

Andy Murray, the third seed, will be playing for more history as he continues his title defence with a test against big-hitting South African Kevin Anderson.

"It's been a good start, for sure," said the player who has gone through in straight sets so far. "I played well from the first game of the first match pretty much through until the end of the third round.

"I haven't used up too much energy, which is good. I don't know if it's the best I've felt.  But it's been a good first week."

Roger Federer hopes to take his bid for a record eighth title a step further after a blemish-free opening week.

"I'm pleased, absolutely.  It's been a good first week for me," said the Swiss. "I've been playing well, been feeling good.  Didn't drop any sets.  Wasn't really in danger in any of the matches.

"I totally got a lot of info from the first week, how I need to play moving forward."

With Williams and number two Li Na out, Roland Garros finalist Simona Halep is the highest seed remaining on third. She plays Kazakh Zarina Diyas.

Former finalist Agnieszka Radwanska,the fourth seed, takes on Ekaterina Makarova, and sixth-seeded 2011 champion Petra Kvitova faces China's Peng Shuai.